7-Methoxyflavone

7-Methoxyflavone

SCHEMBL28098795

CCCC[Sn](=O)CCCC.COc1ccc2c(=O)cc(-c3ccccc3)oc2c1

nearest known ligand 0.73

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 2/20 0.73
CYP19A1 P11511 1/20 0.73
MAOB P27338 4/20 0.62
KDM4E B2RXH2 6/20 0.61
CYP3A4 P08684 5/20 0.61
ALDH1A1 P00352 5/20 0.61
HPGD P15428 4/20 0.61
HSD17B10 Q99714 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
ABCB1 P08183 1/20 0.61
ABCG2 Q9UNQ0 1/20 0.61
USP2 O75604 1/20 0.61
MAPK1 P28482 1/20 0.61
RECQL P46063 1/20 0.61
ACHE P22303 1/20 0.59
MAPT P10636 4/20 0.57
TP53 P04637 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP2C9 P11712 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7-Methoxyflavone SCHEMBL1373009 0.86 TNKS (1.00) TNKSCYP19A1MAOBKDM4ECYP3A4
SCHEMBL31238410 0.78 TNKS (0.84) TNKSCYP19A1MAOBKDM4ECYP3A4
4,7-Dimethoxyflavone SCHEMBL3470601 0.78 MAOB (1.00) TNKSCYP19A1MAOBKDM4ECYP3A4
SCHEMBL10025659 0.77 SIGMAR1 (0.76) TNKSCYP19A1KDM4ECYP3A4SMN1; SMN2
SCHEMBL9140701 0.77 KDM4E (0.74) TNKSCYP19A1MAOBKDM4ECYP3A4
7,3'-Dimethoxyflavone SCHEMBL718068 0.77 KDM4E (1.00) TNKSCYP19A1MAOBKDM4ECYP3A4
6-Methoxyflavone SCHEMBL30799564 0.77 ABCB1 (1.00) TNKSCYP19A1MAOBKDM4ECYP3A4
6-Methoxyflavone SCHEMBL28930176 0.77 ABCB1 (1.00) TNKSCYP19A1MAOBKDM4ECYP3A4
6-Methoxyflavone SCHEMBL312059 0.77 ABCB1 (1.00) TNKSCYP19A1MAOBKDM4ECYP3A4
6-Methoxyflavone SCHEMBL28301080 0.76 ABCB1 (0.97) TNKSCYP19A1MAOBKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106083793-A A kind of preparation method of 7 methoxy flavones 嘉兴学院 2016-11-09 CN disclosed