Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730491 | 0.91 | HPRT1 (0.41) | ALOX15HSD17B10CYP3A4ALDH1A1ALOX12 | |
| SCHEMBL13730705 | 0.90 | ALOX15 (0.44) | ALOX15HSD17B10CYP3A4ALDH1A1ALOX12 | |
| SCHEMBL9009109 | 0.86 | ALDH1A1 (0.40) | ALOX15HSD17B10CYP3A4ALDH1A1ALOX12 | |
| SCHEMBL9009067 | 0.86 | ALOX15 (0.43) | ALOX15HSD17B10CYP3A4ALDH1A1ALOX12 | |
| SCHEMBL27312853 | 0.84 | HPRT1 (0.63) | HSD17B10CYP3A4ALDH1A1HPGDTRPM4 | |
| SCHEMBL31229508 | 0.81 | PLAU (0.48) | ALOX15HSD17B10CYP3A4ALDH1A1HPGD | |
| SCHEMBL7245676 | 0.78 | ALDH1A1 (0.58) | HSD17B10CYP3A4ALDH1A1HPGDTRPM4 | |
| SCHEMBL5605839 | 0.77 | ALDH1A1 (0.46) | ALOX15HSD17B10CYP3A4ALDH1A1ALOX12 | |
| SCHEMBL5606122 | 0.77 | ALDH1A1 (0.46) | ALOX15HSD17B10CYP3A4ALDH1A1ALOX12 | |
| SCHEMBL9627309 | 0.77 | NT5E (0.45) | HSD17B10ALDH1A1GAAMAPTNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140047976-A1 | Cardo-Polybenzoxazole Polymer/Copolymer Membranes For Improved Permeability And Method For Fabricating The Same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-02-20 | — | — | US | disclosed |
| WO-2012148360-A1 | CARDO-POLYBENZOXAZOLE POLYMER/COPOLYMER MEMBRANES FOR IMPROVED PERMEABILITY AND METHOD FOR FABRICATING THE SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-11-01 | — | — | WO | disclosed |