Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.48 |
| ▸ | CDK2 | P24941 | 7/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015389 | 0.77 | DEGS1 (0.48) | DEGS1EPHX2CCNE1CDK2CDK5 | |
| SCHEMBL16061776 | 0.73 | EPHX2 (0.50) | DEGS1EPHX2CCNE1CDK2CDK5 | |
| SCHEMBL2492016 | 0.73 | EPHX2 (0.58) | DEGS1EPHX2CCNE1CDK2CDK5 | |
| SCHEMBL822338 | 0.72 | TSHR (0.59) | EPHX2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13934555 | 0.70 | EPHX2 (0.53) | DEGS1EPHX2CCNE1CDK2CDK5 | |
| SCHEMBL20284048 | 0.70 | DEGS1 (1.00) | DEGS1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL4433540 | 0.69 | HPGD (0.67) | EPHX2MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL29511368 | 0.69 | HPGD (0.67) | EPHX2MEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL1674143 | 0.69 | DEGS1 (0.71) | DEGS1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL1516167 | 0.68 | EPHX2 (1.00) | EPHX2CA1CA2CA5ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |