SCHEMBL29511368

SCHEMBL29511368

O=C(Cc1ccccc1)Nc1ccccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.67
ALDH1A1 P00352 5/20 0.65
LMNA P02545 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
KDM4E B2RXH2 1/20 0.64
EPHX2 P34913 1/20 0.61
KMT2A Q03164 5/20 0.59
GAA P10253 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
ATM Q13315 1/20 0.59
MAPT P10636 2/20 0.56
KCNQ2 O43526 1/20 0.56
PKM P14618 1/20 0.56
CRHBP P24387 1/20 0.56
CRHR2 Q13324 1/20 0.56
HDAC3 O15379 1/20 0.56
MEN1 O00255 2/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
KDM1A O60341 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4433540 1.00 HPGD (0.67) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL14030871 0.82 CRHBP (0.51) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL13416408 0.82 KDM1A (0.68) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL11900441 0.81 ALDH1A1 (0.70) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL14030915 0.81 MAPT (0.50) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL4361189 0.81 KDM1A (0.62) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL7734705 0.80 MAPK1 (0.74) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL554401 0.80 CA1 (0.54) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL29354065 0.80 CA1 (0.54) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL15437984 0.80 KMT2A (0.77) HPGDALDH1A1LMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11608394-B2 Nanoparticles and formulations for printing YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-21 US claimed
EP-4703470-A1 CELLULASE VARIANTS AB Enzymes Finland Oy (FI) 2026-03-04 EP disclosed
US-12545720-B2 Anti-alpha-synuclein antibodies UCB Biopharma SRL (BE) 2026-02-10 US disclosed
US-12410244-B2 Anti-alpha-synuclein antibodies UCB Biopharma SRL (BE) 2025-09-09 US disclosed
US-20250277211-A1 LPA inhibitors and uses thereof KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) 2025-09-04 US disclosed
EP-4567112-A1 RNA INHIBITOR FOR INHIBITING APOC3 GENE EXPRESSION AND USE THEREOF Kylonova (Xiamen) Biopharma Co., Ltd. (CN) 2025-06-11 EP disclosed
CN-113862268-B AGT inhibitors and uses thereof 厦门甘宝利生物医药有限公司 2025-05-13 CN disclosed
US-20250066789-A1 AGT Inhibitor and Use Thereof KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) 2025-02-27 US disclosed
EP-4491727-A1 LPA INHIBITOR AND USE THEREOF Kylonova (Xiamen) Biopharma Co., Ltd. (CN) 2025-01-15 EP disclosed
CN-111655727-B Anti-alpha synuclein antibodies UCB生物制药有限责任公司 2024-10-29 CN disclosed
CN-113497633-B Method for improving IP2 index of zero intermediate frequency and low intermediate frequency architecture receiver and architecture thereof 海能达通信股份有限公司 2023-05-09 CN disclosed
WO-2023066236-A1 AGT INHIBITOR AND USE THEREOF 厦门甘宝利生物医药有限公司 2023-04-27 WO disclosed
US-11608394-B2 Nanoparticles and formulations for printing YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-21 US disclosed
US-20220340648-A1 ANTI-ALPHA-SYNUCLEIN ANTIBODIES UCB Biopharma SRL (BE) 2022-10-27 US disclosed
US-11478501-B2 Compositions and methods for inhibiting HMGB1 expression DICERNA PHARMACEUTICALS, INC. (US) 2022-10-25 US disclosed
US-11446383-B2 Lipid formulations for delivery of therapeutic agents ARBUTUS BIOPHARMA CORPORATION (CA) 2022-09-20 US disclosed
US-20220220192-A1 ANTI-ALPHA-SYNUCLEIN ANTIBODIES UCB Biopharma SRL (BE) 2022-07-14 US disclosed
CN-114703184-A LPA inhibitor and use thereof 厦门甘宝利生物医药有限公司 2022-07-05 CN disclosed
CN-114351274-A High-light-fastness polyvinyl chloride composite material for textilene mesh cloth and preparation process of textilene mesh cloth 台州东海塑料品制造有限公司 2022-04-15 CN disclosed
US-11292831-B2 Anti-alpha synuclein antibodies UCB Biopharma SRL (BE) 2022-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220340648-A1 ANTI-ALPHA-SYNUCLEIN ANTIBODIES SNCA, PARK7, SYNJ1 HPGD 4427/4885ALDH1A1 3176/4885LMNA 2421/4885
US-12410244-B2 Anti-alpha-synuclein antibodies SNCA, PARK7, SYNJ1 HPGD 4427/4885ALDH1A1 3176/4885LMNA 2421/4885
US-11446383-B2 Lipid formulations for delivery of therapeutic agents CETP, PNLIP, NPC1L1 HPGD 3969/4885ALDH1A1 1878/4885LMNA 793/4885
US-20220220192-A1 ANTI-ALPHA-SYNUCLEIN ANTIBODIES SNCA, PARK7, SYNJ1 HPGD 4445/4885ALDH1A1 3160/4885LMNA 2475/4885
US-11478501-B2 Compositions and methods for inhibiting HMGB1 expression HMGB1, HMGB3, HMGB2 HPGD 1460/4885ALDH1A1 3787/4885LMNA 480/4885
US-12545720-B2 Anti-alpha-synuclein antibodies SNCA, PARK7, CDR2 HPGD 4348/4885ALDH1A1 3372/4885LMNA 1795/4885
US-11292831-B2 Anti-alpha synuclein antibodies SNCA, PARK7, SYNJ1 HPGD 4498/4885ALDH1A1 3587/4885LMNA 2550/4885
US-20250066789-A1 AGT Inhibitor and Use Thereof AGT, AGTR1, AGTR2 HPGD 2694/4885ALDH1A1 2543/4885LMNA 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.