SCHEMBL4433540

SCHEMBL4433540

O=C(Cc1ccccc1)Nc1ccccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.67
ALDH1A1 P00352 5/20 0.65
LMNA P02545 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
KDM4E B2RXH2 1/20 0.64
EPHX2 P34913 1/20 0.61
KMT2A Q03164 5/20 0.59
GAA P10253 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
ATM Q13315 1/20 0.59
MAPT P10636 2/20 0.56
KCNQ2 O43526 1/20 0.56
PKM P14618 1/20 0.56
CRHBP P24387 1/20 0.56
CRHR2 Q13324 1/20 0.56
HDAC3 O15379 1/20 0.56
MEN1 O00255 2/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
KDM1A O60341 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511368 1.00 HPGD (0.67) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL14030871 0.82 CRHBP (0.51) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL13416408 0.82 KDM1A (0.68) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL11900441 0.81 ALDH1A1 (0.70) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL14030915 0.81 MAPT (0.50) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL4361189 0.81 KDM1A (0.62) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL7734705 0.80 MAPK1 (0.74) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL554401 0.80 CA1 (0.54) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL29354065 0.80 CA1 (0.54) HPGDALDH1A1LMNASMN1; SMN2KDM4E
SCHEMBL15437984 0.80 KMT2A (0.77) HPGDALDH1A1LMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187788-B2 Photosensitive resin composition and photosensitive film ASAHI KASEI KABUSHIKI KAISHA (JP) 2012-05-29 US disclosed
US-20090191385-A1 Photosensitive Resin Composition and Photosensitive Film ASAHI KASEI KABUSHIKI KAISHA (JP) 2009-07-30 US disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed