SCHEMBL1373253

SCHEMBL1373253

CN(c1ccc2c(O)cc(S(=O)(=O)O)cc2c1)S(=O)(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 3/20 0.61
CASP6 P55212 5/20 0.57
DUSP3 P51452 2/20 0.57
PTPN5 P54829 2/20 0.57
PTPN11 Q06124 2/20 0.57
PRMT1 Q99873 2/20 0.57
NT5E P21589 3/20 0.47
CTDSP1 Q9GZU7 1/20 0.45
SIRT1 Q96EB6 1/20 0.42
CASP7 P55210 1/20 0.41
ALDH1A1 P00352 4/20 0.39
CYP2C9 P11712 3/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3894493 0.88 NSD2 (0.78) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL27138366 0.88 NSD2 (0.78) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL10384211 0.83 NSD2 (0.52) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL7720118 0.83 NSD2 (0.58) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL27425514 0.83 NSD2 (0.58) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL10894768 0.81 CASP6 (0.56) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL6559615 0.81 NSD2 (0.50) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL29462031 0.81 CASP6 (0.77) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL465086 0.81 CASP6 (0.77) NSD2CASP6DUSP3PTPN5PTPN11
SCHEMBL18274858 0.79 CASP6 (0.74) NSD2CASP6DUSP3PTPN5PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2391683-B1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DISTRIB GMBH (DE) 2017-03-29 EP disclosed
US-9062208-B2 Fiber-reactive copper complex disazo dyes DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-06-23 US disclosed
EP-1490441-B2 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-12-26 EP disclosed
US-20110283465-A1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-11-24 US disclosed
EP-1789499-B1 DYE MIXTURES OF FIBRE-REACTIVE AZO DYES PRODUCTION AND USE THEREOF DYSTAR COLOURS DEUTSCHLAND (DE) 2011-03-23 EP disclosed
WO-2010086243-A2 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2010-08-05 WO disclosed
US-7708786-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2010-05-04 US disclosed
US-7704287-B2 Reactive red dye composition and application thereof EVERLIGHT USA, INC. (US) 2010-04-27 US disclosed
US-7637964-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2009-12-29 US disclosed
US-20090025152-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2009-01-29 US disclosed
US-20050166339-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO.DEUTSCHLAND KG (DE) 2005-08-04 US disclosed
US-20050150063-A1 Fiber-reactive azo dyes, preparation thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-07-14 US disclosed
EP-1508598-A1 Mixture of fiberreactive azo dyes process for their preparation and use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 EP disclosed
EP-1508596-A1 Mixtures of azo reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 EP disclosed
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2005-02-17 US disclosed
US-20050034253-A1 Mixture; ink for ink jet printing DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-02-17 US disclosed
EP-1499681-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-01-26 EP disclosed
EP-1490441-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-12-29 EP disclosed
WO-2003089521-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-30 WO disclosed
WO-2003080739-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use CRY1, FZD7, CBR3 NSD2 628/4885CASP6 2589/4885DUSP3 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.