SCHEMBL13732602

SCHEMBL13732602

CCCC(Oc1ccc(F)c(C(N)=O)c1F)c1nc(-c2ccc(Cl)cc2)c(Br)o1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 11/20 0.35
FPR2 P25090 2/20 0.35
TARBP2 Q15633 1/20 0.31
CTSA P10619 1/20 0.31
PPARG P37231 2/20 0.30
PPARA Q07869 2/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13733148 0.93 SCN9A (0.34) SCN9AFPR2TARBP2CTSA
SCHEMBL18286459 0.92 TARBP2 (0.32) SCN9AFPR2TARBP2CTSAPPARG
SCHEMBL19210474 0.90 RXRA (0.34) SCN9AFPR2CTSA
SCHEMBL13733585 0.90 SCN9A (0.35) SCN9AFPR2CTSACNR1
SCHEMBL15711806 0.89 SCN9A (0.33) SCN9AFPR2CTSA
SCHEMBL13731862 0.89 SCN9A (0.35) SCN9AFPR2TARBP2CTSA
SCHEMBL13732764 0.88 FPR2 (0.33) SCN9AFPR2TARBP2CTSA
SCHEMBL15675498 0.87 SCN9A (0.31) SCN9AFPR2
SCHEMBL13731448 0.86 FPR2 (0.33) SCN9AFPR2
SCHEMBL13731419 0.86 SCN9A (0.37) SCN9AFPR2CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140135332-A1 AROMATIC AMIDES AND USES THEREOF BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2014-05-15 US claimed
EP-2699557-A1 AROMATIC AMIDES AND USES THEREOF Biota Scientific Management Pty Ltd (AU) 2014-02-26 EP claimed
WO-2012142671-A1 AROMATIC AMIDES AND USES THEREOF BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-10-26 WO claimed
EP-2699557-B1 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS BIOTA SCIENT MANAGEMENT (AU) 2017-08-16 EP disclosed
US-9511073-B2 Aromatic amides and uses thereof TAXIS PHARMACEUTICALS, INC. (US) 2016-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135332-A1 AROMATIC AMIDES AND USES THEREOF NAT1, ASNS, CYP2C9 SCN9A 891/4885FPR2 920/4885TARBP2 3956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.