Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | RXRG | P48443 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 3/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210456 | 0.91 | RXRA (0.35) | RXRARXRBRXRGFFAR4DHODH | |
| SCHEMBL13734658 | 0.91 | PTPN1 (0.34) | RXRARXRBRXRGFFAR4DHODH | |
| SCHEMBL19210393 | 0.91 | MAPT (0.35) | FFAR4CTSAPTGDR2 | |
| SCHEMBL13732602 | 0.90 | SCN9A (0.35) | CTSAFPR2SCN9A | |
| SCHEMBL19210438 | 0.90 | IMPDH2 (0.33) | FFAR4CTSAPTGDR2SCN9A | |
| SCHEMBL19210449 | 0.89 | FFAR4 (0.36) | FFAR4DHODHCTSAFPR2SCN9A | |
| SCHEMBL19210419 | 0.89 | CTSA (0.34) | CTSAPTGDR2 | |
| SCHEMBL13733585 | 0.89 | SCN9A (0.35) | DHODHCTSAFPR2SCN9A | |
| SCHEMBL13733148 | 0.88 | SCN9A (0.34) | DHODHCTSAPTGDR2FPR2SCN9A | |
| SCHEMBL19210395 | 0.87 | S1PR1 (0.36) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |