Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 2/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795096 | 0.92 | ALDH1A1 (0.42) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL30608945 | 0.71 | USP30 (0.43) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL30324508 | 0.66 | GAA (0.40) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL5010541 | 0.66 | ALDH1A1 (0.51) | CHRNA7HTR3AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6043826 | 0.66 | CTSV (0.46) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL4158989 | 0.65 | ABHD6 (0.47) | ALDH1A1MEN1KMT2ADPP4NPC1 | |
| SCHEMBL12500075 | 0.64 | HRH1 (0.38) | ALDH1A1SLC6A2SLC6A3NPC1RAB9A | |
| SCHEMBL11418804 | 0.63 | MEN1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL16795099 | 0.62 | EPHX2 (0.33) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL5271411 | 0.62 | EPHX2 (0.59) | SCD5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416962-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS | SANOFI (FR) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140669-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS | SANOFI (FR) | 2017-08-24 | — | — | WO | disclosed |
| EP-2702059-A1 | NOVEL COMPOUND USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | Galapagos N.V. (BE) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012146659-A1 | NOVEL COMPOUND USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2012-11-01 | — | — | WO | disclosed |