SCHEMBL1373609

SCHEMBL1373609

CC(C)COOC(=O)/C=C/c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
ALDH1A1 P00352 2/20 0.50
AKR1B10 O60218 3/20 0.48
AKR1B1 P15121 3/20 0.48
TDP1 Q9NUW8 2/20 0.47
GLA P06280 1/20 0.47
KMT2A Q03164 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 2/20 0.46
HDAC3 O15379 1/20 0.46
TNKS O95271 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1373613 1.00 LMNA (0.50) LMNAALDH1A1AKR1B10AKR1B1TDP1
Isobutyl Cinnamate SCHEMBL868714 0.84 LMNA (0.61) LMNAALDH1A1AKR1B10AKR1B1TDP1
Isobutyl Cinnamate SCHEMBL868715 0.84 LMNA (0.61) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL5013109 0.82 ALDH1A1 (0.49) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL5013117 0.82 ALDH1A1 (0.49) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL6244908 0.82 LMNA (0.54) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL6244901 0.82 LMNA (0.54) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL28637583 0.82 ALDH1A1 (0.48) LMNAALDH1A1AKR1B10AKR1B1TDP1
SCHEMBL8750906 0.81 LMNA (0.47) LMNAALDH1A1AKR1B10AKR1B1TDP1
Isobutyl Cinnamate SCHEMBL14763629 0.80 HDAC3 (0.58) LMNAALDH1A1AKR1B10AKR1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575750-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE International Flora Technologies, Ltd. (US) 2013-04-10 EP claimed
WO-2011149929-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-12-01 WO claimed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US claimed
WO-2025133665-A1 OIL-IN-WATER EMULSION L V M H RECHERCHE (FR) 2025-06-26 WO disclosed
EP-4452208-A1 AQUEOUS EMULSION L V M H RECHERCHE (FR) 2024-10-30 EP disclosed
WO-2023118912-A1 AQUEOUS EMULSION L V M H RECHERCHE (FR) 2023-06-29 WO disclosed
US-20230040911-A1 Oil-In-Water-Type Emulsion Cosmetic L V M H RECHERCHE (FR) 2023-02-09 US disclosed
EP-4076348-A1 OIL-IN-WATER-TYPE EMULSION COSMETIC L V M H RECHERCHE (FR) 2022-10-26 EP disclosed
WO-2021151452-A1 OIL-IN-WATER-TYPE EMULSION COSMETIC L V M H RECHERCHE (FR) 2021-08-05 WO disclosed
EP-2575750-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE International Flora Technologies, Ltd. (US) 2013-04-10 EP disclosed
WO-2011149929-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-12-01 WO disclosed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040911-A1 Oil-In-Water-Type Emulsion Cosmetic CUTA, PHOSPHO1, LIPE LMNA 874/4885ALDH1A1 4132/4885AKR1B10 3453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.