Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 9/20 | 0.37 |
| ▸ | NOS2 | P35228 | 8/20 | 0.37 |
| ▸ | NOS3 | P29474 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303475 | 0.83 | ENPP2 (0.43) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL31662833 | 0.76 | ALDH1A1 (0.48) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL348900 | 0.76 | ALDH1A1 (0.48) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL13736565 | 0.76 | GBA1 (0.43) | GBA1ALDH1A1 | |
| SCHEMBL2388264 | 0.75 | ENPP2 (0.44) | PNMTENPP2LOXL2NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL25180658 | 0.74 | ALDH1A1 (0.47) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL3510031 | 0.73 | ALDH1A1 (0.55) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL20553480 | 0.72 | HIF1A (0.50) | ALDH1A1 | |
| SCHEMBL13736169 | 0.72 | KCNN4 (0.41) | GBA1ENPP2ALDH1A1 | |
| SCHEMBL21649568 | 0.72 | PNMT (0.44) | PNMTENPP2LOXL2NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | disclosed |