SCHEMBL303475

SCHEMBL303475

CN(CC(O)CN(C)c1cccc(CN)c1)c1cccc(CN)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 1/20 0.43
▸ NOS1 P29475 6/20 0.40
▸ NOS2 P35228 6/20 0.40
▸ PRMT5 O14744 2/20 0.39
▸ WDR77 Q9BQA1 1/20 0.39
▸ NOS3 P29474 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ PNMT P11086 1/20 0.39
▸ LOXL2 Q9Y4K0 3/20 0.39
▸ CETP P11597 3/20 0.38
▸ KDM4E B2RXH2 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ SIGMAR1 Q99720 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20553480 0.84 HIF1A (0.50) PRMT5WDR77ALDH1A1CETP
SCHEMBL13736137 0.83 GBA1 (0.44) ENPP2NOS1NOS2NOS3ALDH1A1
SCHEMBL2388264 0.78 ENPP2 (0.44) ENPP2NOS1NOS2NOS3ALDH1A1
SCHEMBL348900 0.76 ALDH1A1 (0.48) ENPP2NOS1NOS2NOS3ALDH1A1
SCHEMBL31662833 0.76 ALDH1A1 (0.48) ENPP2NOS1NOS2NOS3ALDH1A1
Hydrochloric Acid SCHEMBL25180658 0.74 ALDH1A1 (0.47) ENPP2NOS1NOS2NOS3ALDH1A1
SCHEMBL9379744 0.72 AOC3 (0.50) ALDH1A1CYP3A4CETP
SCHEMBL8857146 0.72 SLC6A2 (0.49) KDM4EL3MBTL1
SCHEMBL21649568 0.72 PNMT (0.44) ENPP2NOS1NOS2NOS3ALDH1A1
SCHEMBL16274690 0.71 CRHBP (0.46) ENPP2NOS1NOS2NOS3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120205591-A1 SELF INDICATING RADIATION ALERT DOSIMETER PATEL GORDHABHAI N (US) 2012-08-16 — — US claimed
JP-4852410-B2 — — 2012-01-11 — — JP claimed
US-7476874-B2 Self indicating radiation alert dosimeter JP LABORATORIES, INC. (US) 2009-01-13 — — US claimed
US-20060145091-A1 Self indicating radiation alert dosimeter JP LABORATORIES INC. 2006-07-06 — — US claimed
EP-1599744-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES, INC. (US) 2005-11-30 — — EP claimed
WO-2004077097-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES INC. (US) 2004-09-10 — — WO claimed
US-20170023681-A1 PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER NEW YORK UNIVERSITY 2017-01-26 — — US disclosed
US-9086489-B2 Personal and area self-indicating instant radiation alert dosimeter JP LABORATORIES, INC (US) 2015-07-21 — — US disclosed
US-8872134-B2 Self indicating radiation alert dosimeter JP LABORATORIES, INC (US) 2014-10-28 — — US disclosed
US-20120205591-A1 SELF INDICATING RADIATION ALERT DOSIMETER PATEL GORDHABHAI N (US) 2012-08-16 — — US disclosed
US-20120181453-A1 PERSONAL AND AREA SELF-INDICATING INSTANT RADIATION ALERT DOSIMETER JP LABORATORIES INC. 2012-07-19 — — US disclosed
US-8115182-B1 Personal and area self-indicating radiation alert dosimeter JP LABORATORIES INC. 2012-02-14 — — US disclosed
US-7476874-B2 Self indicating radiation alert dosimeter JP LABORATORIES, INC. (US) 2009-01-13 — — US disclosed
US-7227158-B1 Stick-on self-indicating instant radiation dosimeter JP LABS, INC. (US) 2007-06-05 — — US disclosed
US-20060145091-A1 Self indicating radiation alert dosimeter JP LABORATORIES INC. 2006-07-06 — — US disclosed
EP-1599744-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES, INC. (US) 2005-11-30 — — EP disclosed
WO-2004077097-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES INC. (US) 2004-09-10 — — WO disclosed
Send feedback