Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.52 |
| ▸ | MTOR | P42345 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402425 | 0.82 | RAB9A (0.60) | MEN1KMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL6354575 | 0.79 | PIK3CA (0.61) | PIK3CAPIK3CDPIK3CGPIK3CBMTOR | |
| SCHEMBL884758 | 0.78 | KCNA5 (0.49) | PIK3CAPIK3CDPIK3CGPIK3CBMTOR | |
| SCHEMBL9402419 | 0.78 | MEN1 (0.63) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL1372451 | 0.77 | MEN1 (0.56) | PIK3CAPIK3CDPIK3CGPIK3CBMTOR | |
| SCHEMBL9402356 | 0.77 | DHODH (0.57) | KMT2AUSP2KDM4EMAPTTSHR | |
| SCHEMBL10094233 | 0.77 | PIK3CA (0.53) | PIK3CAPIK3CDPIK3CGPIK3CBMTOR | |
| SCHEMBL1375752 | 0.76 | PIK3CA (0.52) | PIK3CAPIK3CDPIK3CGPIK3CBMTOR | |
| SCHEMBL10681018 | 0.76 | ALDH1A1 (0.52) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2284031 | 0.75 | KMT2A (0.50) | PIK3CAPIK3CDPIK3CGPIK3CBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394995-B1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| EP-2394995-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | Kumiai Chemical Industry CO., LTD. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | PIK3CA 2282/4885PIK3CD 2602/4885PIK3CG 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.