Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402419 | 0.85 | MEN1 (0.63) | RAB9ANPC1HTTALDH1A1MAPT | |
| SCHEMBL1373989 | 0.82 | PIK3CA (0.52) | RAB9ANPC1HTTNPSR1ALDH1A1 | |
| SCHEMBL1375014 | 0.81 | DHODH (0.56) | RAB9ANPC1HTTNPSR1ALDH1A1 | |
| SCHEMBL9402356 | 0.80 | DHODH (0.57) | RAB9ANPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL9402422 | 0.80 | RAB9A (0.57) | RAB9ANPC1HTTALDH1A1MAPT | |
| SCHEMBL10681018 | 0.79 | ALDH1A1 (0.52) | RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28142607 | 0.77 | RAB9A (0.64) | RAB9ANPC1HTTNPSR1ALDH1A1 | |
| SCHEMBL29384795 | 0.77 | RAB9A (0.61) | RAB9ANPC1HTTNPSR1ALDH1A1 | |
| SCHEMBL31451657 | 0.77 | RAB9A (0.61) | RAB9ANPC1HTTNPSR1ALDH1A1 | |
| SCHEMBL5322920 | 0.77 | RAB9A (0.61) | RAB9ANPC1HTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364860-A | Naphthyridine compounds which inhibit tyrosine kinase and their pharmaceutical compositions | LABORATOIRES UPSA (FR) | 1994-11-15 | — | — | US | disclosed |
| US-4786642-A | ANTIULCER | SOCIETE ANONYME: CARPIBEM (FR) | 1988-11-22 | — | — | US | disclosed |