Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615884 | 0.75 | HDAC3 (0.47) | CYP1A2CYP2C19HDAC3 | |
| SCHEMBL17061192 | 0.73 | MGLL (0.43) | — | |
| SCHEMBL1128054 | 0.69 | HDAC3 (0.48) | CYP1A2CYP2C19KDM4ETSHRALDH1A1 | |
| SCHEMBL10489558 | 0.69 | HDAC3 (0.48) | PARP1HDAC3 | |
| SCHEMBL14166796 | 0.69 | HDAC3 (0.48) | PARP1HDAC3 | |
| SCHEMBL25435570 | 0.69 | HDAC3 (0.51) | PARP1HDAC3 | |
| SCHEMBL28241677 | 0.69 | HDAC3 (0.48) | PARP1HDAC3 | |
| SCHEMBL497070 | 0.69 | HDAC3 (0.46) | TSHRSIGMAR1HDAC3 | |
| SCHEMBL11836606 | 0.68 | ALDH1A1 (0.49) | CYP1A2CYP2C9CYP2C19KDM4ETSHR | |
| SCHEMBL4553128 | 0.68 | NAMPT (0.45) | KDM4ETSHRALDH1A1PKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012155022-A1 | NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-11-15 | — | — | WO | disclosed |