Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756089 | 0.84 | MAPT (0.38) | ALDH1A3ALDH1A1L3MBTL1 | |
| SCHEMBL9715199 | 0.81 | MEN1 (0.47) | ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL7150417 | 0.79 | TP53 (0.41) | ALDH3A1ALDH1A3ALDH1A1TP53CRHR1 | |
| SCHEMBL9107947 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TP53CRHR1DRD3NPSR1 | |
| SCHEMBL27758113 | 0.75 | TDP1 (0.37) | ALDH1A1TP53NPSR1ESR1 | |
| SCHEMBL14511099 | 0.74 | SIGMAR1 (0.33) | ALDH1A1TP53L3MBTL1 | |
| SCHEMBL4977180 | 0.74 | ALDH3A1 (0.40) | ALDH3A1ALDH1A3ALDH1A1TP53CRHR1 | |
| SCHEMBL30462984 | 0.74 | HTR1A (0.40) | ALDH3A1ALDH1A3ALDH1A1TP53CRHR1 | |
| SCHEMBL5167326 | 0.73 | HTR1A (0.37) | ALDH3A1ALDH1A3ALDH1A1TP53CRHR1 | |
| SCHEMBL23349106 | 0.73 | TSHR (0.39) | ALDH3A1ALDH1A3ALDH1A1TP53CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579365-B2 | Indolyl-3-glyoxylic acid derivatives having antitumor action | ZIOPHRAM ONCOLOGY, INC. (US) | 2009-08-25 | — | — | US | disclosed |