Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4227267 | 0.80 | MAPT (0.34) | GNRHRCCR4KCNQ3KCNQ2 | |
| SCHEMBL4228174 | 0.70 | GNRHR (0.34) | GNRHR | |
| SCHEMBL4233244 | 0.70 | GNRHR (0.34) | GNRHR | |
| SCHEMBL4233356 | 0.69 | GNRHR (0.35) | GNRHR | |
| SCHEMBL4227494 | 0.68 | KCNH3 (0.31) | — | |
| SCHEMBL4237708 | 0.67 | GNRHR (0.33) | GNRHR | |
| SCHEMBL4233139 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL23094553 | 0.59 | HCAR3 (0.35) | — | |
| SCHEMBL4233289 | 0.59 | GNRHR (0.35) | GNRHRKCNQ3KCNQ2 | |
| SCHEMBL4621627 | 0.59 | MAP3K5 (0.40) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209522-A1 | Heterocyclic Non-Peptide GNRH Antagonists | TAKEDA CAMBRIDGE LIMITED (GB) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209522-A1 | Heterocyclic Non-Peptide GNRH Antagonists | GNRHR, GHRHR, FSHR | GNRHR 1/4885CCR4 681/4885KCNQ3 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.