Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 7/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11947977 | 0.89 | CTRB1 (0.55) | ATML3MBTL1CMA1ACETACR1 | |
| SCHEMBL29467321 | 0.86 | F2 (0.45) | FAPOPRD1 | |
| SCHEMBL31113348 | 0.86 | PSMB9 (0.46) | FAPPSMB9OPRD1 | |
| SCHEMBL30139062 | 0.84 | F2 (0.43) | FAPOPRM1OPRD1 | |
| SCHEMBL28559438 | 0.82 | F2 (0.46) | ACEOPRD1 | |
| SCHEMBL31297113 | 0.82 | F2 (0.47) | FAPACEOPRM1 | |
| SCHEMBL31258873 | 0.82 | OPRD1 (0.49) | FAPACEACE2OPRD1 | |
| SCHEMBL21462327 | 0.82 | OPRD1 (0.49) | FAPACEACE2OPRD1 | |
| SCHEMBL29444020 | 0.82 | OPRD1 (0.49) | FAPACEACE2OPRD1 | |
| SCHEMBL29868206 | 0.82 | CTRB1 (0.56) | CMA1ACETACR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215093-A1 | COMPOUNDS FOR ENZYME INHIBITION | PROTEOLIX, INC. (US) | 2009-08-27 | — | — | US | disclosed |