Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467321 | 0.97 | F2 (0.45) | F2FAPOPRD1MDM4TP53 | |
| SCHEMBL30139020 | 0.92 | FDFT1 (0.42) | F2FAPOPRD1MDM4TP53 | |
| SCHEMBL31113348 | 0.88 | PSMB9 (0.46) | F2FAPOPRD1MDM4TP53 | |
| SCHEMBL2946630 | 0.88 | FAP (0.40) | F2FAPOPRD1FDFT1CASP3 | |
| SCHEMBL31297113 | 0.86 | F2 (0.47) | F2FAPFDFT1OPRM1TLR2 | |
| SCHEMBL30445992 | 0.86 | CASP3 (0.39) | F2FAPOPRD1FDFT1CASP3 | |
| SCHEMBL29749447 | 0.86 | CTRB1 (0.48) | F2MDM4TP53FDFT1KMT2A | |
| SCHEMBL30034009 | 0.86 | OPRD1 (0.47) | F2FAPOPRD1PREPKMT2A | |
| SCHEMBL13743328 | 0.84 | FAP (0.49) | FAPOPRD1OPRM1 | |
| SCHEMBL21462327 | 0.83 | OPRD1 (0.49) | F2FAPOPRD1PREPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181173-A | Preparation method of Tirzepatide | 深圳市健元医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |