Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241577 | 0.87 | PNMT (0.33) | PNMT | |
| SCHEMBL13328155 | 0.82 | SIGMAR1 (0.36) | ADORA1SIGMAR1PNMTPTPRCPTPN2 | |
| SCHEMBL13030302 | 0.79 | ADORA1 (0.43) | ADORA1SIGMAR1PNMTPTPRCPTPN2 | |
| SCHEMBL22313333 | 0.78 | ADORA1 (0.39) | ADORA1SIGMAR1PTPRCPTPN2PTPN1 | |
| SCHEMBL1292073 | 0.74 | ADORA1 (0.48) | ADORA1SIGMAR1PNMTPTPRCPTPN2 | |
| SCHEMBL13832365 | 0.74 | ADORA1 (0.40) | ADORA1SIGMAR1PNMTPTPRCPTPN2 | |
| SCHEMBL13360470 | 0.73 | HSD17B10 (0.36) | — | |
| SCHEMBL19359600 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL13360484 | 0.72 | ALOX15 (0.35) | — | |
| SCHEMBL13360490 | 0.69 | KDM4E (0.37) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572784-B2 | Compounds and methods for inhibiting mitotic progression | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-08-11 | — | — | US | disclosed |