Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DTYMK | P23919 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12084970 | 0.95 | GRIN2B (0.42) | GRIN2BGRIN2CEPHX1BUB1BCHE | |
| SCHEMBL27078006 | 0.83 | USP30 (0.36) | GRIN2BGRIN2CKDM4EMAPTTHRB | |
| SCHEMBL14445526 | 0.79 | HSD11B1 (0.36) | GRIN2BGRIN2CKDM4EMAPTTHRB | |
| SCHEMBL14117581 | 0.77 | GPR119 (0.39) | LMNAKDM4EMAPTTHRBSMN1; SMN2 | |
| SCHEMBL14117673 | 0.77 | BCHE (0.41) | BCHEDTYMKUSP30 | |
| SCHEMBL14117596 | 0.76 | STS (0.37) | LMNAHPGDMAPTUSP2SMN1; SMN2 | |
| SCHEMBL3407611 | 0.76 | NPFFR1 (0.46) | USP2 | |
| SCHEMBL14117531 | 0.75 | BACE1 (0.41) | LMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL14117689 | 0.74 | GPR119 (0.53) | LMNAMAPTSMN1; SMN2USP30 | |
| SCHEMBL14117683 | 0.74 | BCHE (0.39) | GRIN2BGRIN2CBCHEDTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | GRIN2B 4513/4885GRIN2C 4612/4885EPHX1 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.