Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.54 |
| ▸ | LDHB | P07195 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744250 | 1.00 | LDHA (0.54) | LDHALDHBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4238503 | 1.00 | LDHA (0.54) | LDHALDHBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4237768 | 0.83 | LDHA (0.57) | LDHALDHBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4241399 | 0.83 | LDHA (0.57) | LDHALDHBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4238229 | 0.79 | KMT2A (0.51) | KMT2AMEN1ALDH1A1PAX8LMNA | |
| SCHEMBL4242864 | 0.79 | NPC1 (0.50) | LDHAKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL4244324 | 0.79 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL4380936 | 0.75 | LDHA (0.49) | LDHALDHBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4384687 | 0.75 | LDHA (0.49) | LDHALDHBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4248057 | 0.75 | LDHA (0.49) | LDHALDHBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | LDHA 3026/4885LDHB 2683/4885KMT2A 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.