Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430270 | 0.87 | ALDH1A1 (0.46) | KMT2AALDH1A1CYP1A2MAPTNPC1 | |
| SCHEMBL3400613 | 0.85 | NCF1 (0.44) | KMT2AALDH1A1CYP1A2MAPTNPC1 | |
| SCHEMBL14393798 | 0.84 | GNAI3 (0.47) | KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL14611310 | 0.84 | ALDH1A1 (0.43) | KMT2AALDH1A1CYP1A2CYP2D6RAB9A | |
| SCHEMBL10313328 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1CYP1A2MAPTNPC1 | |
| SCHEMBL7706487 | 0.82 | ALDH1A1 (0.60) | KMT2AALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL22732630 | 0.82 | ALDH1A1 (0.46) | KMT2AALDH1A1CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL21430676 | 0.82 | ALDH1A1 (0.42) | KMT2AALDH1A1CYP1A2MAPTPOLB | |
| SCHEMBL8253329 | 0.82 | ALDH1A1 (0.46) | KMT2AALDH1A1CYP1A2MAPTNPC1 | |
| SCHEMBL3579662 | 0.81 | RAB9A (0.43) | KMT2AALDH1A1MAPTNPC1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-7531537-B2 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | KMT2A 1518/4885ALDH1A1 693/4885CYP1A2 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.