Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14712982 | 0.91 | — | — | |
| SCHEMBL11892671 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SIGMAR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6392070 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL13744440 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SIGMAR1BRD4L3MBTL1KMT2A | |
| SCHEMBL14175000 | 0.81 | SIGMAR1 (0.36) | ALDH1A1SIGMAR1L3MBTL1 | |
| SCHEMBL6608940 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SIGMAR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL24448729 | 0.80 | ALDH1A1 (0.35) | ALDH1A1SIGMAR1HSD11B1KMT2AMEN1 | |
| SCHEMBL24723398 | 0.79 | HSD11B1 (0.39) | ALDH1A1SIGMAR1HSD11B1L3MBTL1KMT2A | |
| SCHEMBL14174999 | 0.79 | ALDH1A1 (0.37) | ALDH1A1SIGMAR1BRD4KMT2AMEN1 | |
| SCHEMBL13745080 | 0.79 | MEN1 (0.41) | ALDH1A1SIGMAR1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | ALDH1A1 693/4885SIGMAR1 781/4885HSD11B1 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.