SCHEMBL13745337

SCHEMBL13745337

CCCN(C=O)CCCN(CC)Cc1cccc(OC)c1-c1cccc(CC(=O)O)c1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BCHE P06276 11/20 0.42
ACHE P22303 8/20 0.41
APP P05067 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3432467 0.80 BCHE (0.39) BCHEACHEAPP
SCHEMBL135067 0.78 BCHE (0.47) BCHEACHE
SCHEMBL135058 0.77 FTO (0.46) BCHEACHE
SCHEMBL137407 0.73 PTGDR2 (0.65)
SCHEMBL137320 0.71 ACHE (0.46) BCHEACHE
SCHEMBL137838 0.70 PTGDR2 (0.63)
SCHEMBL137409 0.70 FTO (0.46) BCHEACHE
SCHEMBL135057 0.66 PTGDR2 (0.56) BCHE
SCHEMBL137837 0.65 KDM4E (0.42)
SCHEMBL153370 0.65 OPRK1 (0.46) BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009099902-A1 N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS AMIRA PHARMACEUTICALS, INC. (US) 2009-08-13 WO disclosed