Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.39 |
| ▸ | ACHE | P22303 | 12/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745337 | 0.80 | BCHE (0.42) | BCHEACHEAPP | |
| SCHEMBL135067 | 0.76 | BCHE (0.47) | BCHEACHEMAOB | |
| SCHEMBL135058 | 0.74 | FTO (0.46) | BCHEACHEMAOB | |
| SCHEMBL137407 | 0.70 | PTGDR2 (0.65) | — | |
| SCHEMBL137320 | 0.69 | ACHE (0.46) | BCHEACHEMAOB | |
| SCHEMBL137838 | 0.67 | PTGDR2 (0.63) | — | |
| SCHEMBL137409 | 0.67 | FTO (0.46) | BCHEACHEMAOB | |
| SCHEMBL135057 | 0.63 | PTGDR2 (0.56) | BCHE | |
| SCHEMBL10702420 | 0.62 | FABP3 (0.50) | — | |
| SCHEMBL2587121 | 0.61 | SELL (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009099902-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |