Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873744 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL505777 | 0.87 | CA1 (0.50) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL9646614 | 0.86 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL28281191 | 0.85 | ALDH1A1 (0.58) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL1161645 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL4763029 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL996608 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL28319093 | 0.82 | ALDH1A1 (0.54) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL18185043 | 0.82 | ALDH1A1 (0.54) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| Alcohol SCHEMBL28228430 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179052-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-05 | — | — | US | disclosed |
| EP-4486735-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-01-08 | — | — | EP | disclosed |
| CN-118786122-A | Herbicidal compounds based on pyrimidinyl-oxy-quinolines | 先正达农作物保护股份公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-115850200-B | Polymerizable 3, 1-benzoxazine substituted phenol monomer, preparation method, cured product and application | 西安交通大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117551057-A | Benzo ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023165874-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |
| EP-3421454-B1 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-04-05 | — | — | EP | disclosed |
| CN-115850200-A | Polymerizable 3, 1-benzoxazine substituted phenol monomer, preparation method, cured product and application | 西安交通大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-108884044-B | Piperidine derivatives | 大塚制药株式会社 | 2023-01-31 | — | — | CN | disclosed |
| WO-2014154762-A1 | DIHYDROQUINAZOLINONE ANALOGUES AS BRD4 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-02 | — | — | WO | disclosed |
| US-20140296230-A1 | DIHYDROQUINAZOLINONE ANALOGUES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2014154762-A1 | DIHYDROQUINAZOLINONE ANALOGUES AS BRD4 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-02 | — | — | WO | disclosed |
| US-20140296230-A1 | DIHYDROQUINAZOLINONE ANALOGUES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140296230-A1 | DIHYDROQUINAZOLINONE ANALOGUES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-2592083-A1 | FUSED QUINAZOLINE DERIVATIVES AND USES THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2013-05-15 | — | — | EP | disclosed |
| US-20110288086-A1 | POLYCYCLIC QUINAZOLINES, PREPARATION THEREOF, AND USE THEREOF | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2011-11-24 | — | — | US | disclosed |
| WO-2001044184-A1 | SYNTHESIS OF INDOLE-CONTAINING SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
| EP-0773944-A1 | BENZYL-IMIDAZOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003403-A1 | BENZYL-IMIDAZOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296230-A1 | DIHYDROQUINAZOLINONE ANALOGUES | MKI67, NQO2, CCNI | ALDH1A1 87/4885ADRA2B 350/4885PTGS1 344/4885 |
| US-20110288086-A1 | POLYCYCLIC QUINAZOLINES, PREPARATION THEREOF, AND USE THEREOF | AURKA, AURKC, AURKB | ALDH1A1 3950/4885ADRA2B 4107/4885PTGS1 4163/4885 |
| US-20250179052-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | PRXL2A, QDPR, PRDX1 | ALDH1A1 351/4885ADRA2B 1309/4885PTGS1 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.