Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.59 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 11/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573468 | 0.93 | AKR1B10 (0.69) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL1573466 | 0.93 | AKR1B10 (0.69) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL13746120 | 0.86 | BACE1 (0.61) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL13311577 | 0.86 | GSK3B (0.65) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL10005951 | 0.85 | MAOB (0.81) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL21778869 | 0.82 | RAB9A (0.68) | MAOBRAB9AMAOAKMT2APOLB | |
| SCHEMBL21998520 | 0.81 | AKR1B10 (0.67) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL3204597 | 0.80 | BACE1 (0.74) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL3204616 | 0.80 | BACE1 (0.74) | MAOBAKR1B1AKR1B10PTGS2GLO1 | |
| SCHEMBL17019815 | 0.79 | ABCB1 (0.76) | MAOBAKR1B1PTGS2GLO1CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572829-B2 | Pharmaceutical compositions useful in prevention and treatment of Beta-amyloid protein-induced disease | KIM DARRICK S H L | 2009-08-11 | — | — | US | disclosed |
| US-20080085932-A1 | Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease | KIM DARRICK S | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085932-A1 | Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease | APP, BACE1, PSEN1 | MAOB 1147/4885AKR1B1 1916/4885AKR1B10 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.