Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 3/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.67 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 5/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237229 | 0.88 | AKR1B10 (0.51) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL30661993 | 0.88 | AKR1B10 (0.51) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL1573466 | 0.87 | AKR1B10 (0.69) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL13310700 | 0.87 | GSK3B (0.58) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL1573468 | 0.87 | AKR1B10 (0.69) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL21778869 | 0.84 | RAB9A (0.68) | MAOBALOX5MMP1MMP2MMP9 | |
| Coumaric Acid SCHEMBL7868662 | 0.81 | AKR1B10 (0.68) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL14629577 | 0.81 | TRPV1 (0.52) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL29489701 | 0.81 | ALOX5 (0.65) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL13745604 | 0.81 | MAOB (0.59) | AKR1B10AKR1B1MAOBPTGS2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | AKR1B10 2189/4885AKR1B1 3189/4885MAOB 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.