Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29224138 | 0.98 | GABRP (0.45) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL27618624 | 0.98 | GABRP (0.45) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL9346315 | 0.91 | GABRA1 (0.50) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL14810067 | 0.91 | GABRA1 (0.50) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL15082410 | 0.90 | CHRM3 (0.44) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Hydrochloric Acid SCHEMBL28832713 | 0.89 | GABRA1 (0.48) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL22445486 | 0.87 | GABRA1 (0.44) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL28063291 | 0.86 | SLC6A1 (0.41) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL23587604 | 0.84 | EPHX1 (0.45) | FABP7FABP5EPHX1CHRM2CHRM4 | |
| SCHEMBL2679235 | 0.84 | EPHX1 (0.45) | FABP7FABP5EPHX1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |