Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618624 | 0.89 | GABRP (0.45) | TSHREPHX1GABRPGABRDGABRA1 | |
| SCHEMBL29224138 | 0.89 | GABRP (0.45) | TSHREPHX1GABRPGABRDGABRA1 | |
| SCHEMBL13746183 | 0.86 | GABRP (0.46) | TSHREPHX1GABRPGABRDGABRA1 | |
| SCHEMBL15082410 | 0.81 | CHRM3 (0.44) | SLC6A1TSHRSLC6A11LMNASMN1; SMN2 | |
| SCHEMBL9346315 | 0.78 | GABRA1 (0.50) | TSHRLMNAKMT2ACYP2D6EPHX1 | |
| SCHEMBL14810067 | 0.78 | GABRA1 (0.50) | TSHRLMNAKMT2ACYP2D6EPHX1 | |
| SCHEMBL2997170 | 0.78 | CHRNB2 (0.56) | LMNASMN1; SMN2MAPTEPHX1FABP7 | |
| SCHEMBL24595803 | 0.78 | EPHX1 (0.48) | TSHRLMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL17061158 | 0.78 | EPHX1 (0.48) | TSHRLMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL17061159 | 0.78 | EPHX1 (0.48) | TSHRLMNASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989321-B | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-111989321-A | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-109843856-A | KRAS G12C inhibitor | 米拉蒂治疗股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-104940202-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-104151312-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |