Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746191 | 0.84 | TP53 (0.68) | KMT2AP2RX7LMNAALDH1A1PKM | |
| SCHEMBL13287103 | 0.83 | GAA (0.68) | KMT2AALDH1A1TP53NPSR1GAA | |
| SCHEMBL21696565 | 0.81 | POLB (0.65) | P2RX7LMNAALDH1A1PKML3MBTL1 | |
| SCHEMBL5246662 | 0.80 | PKM (0.67) | LMNAALDH1A1PKMPLA2G1BATG4B | |
| SCHEMBL5244196 | 0.80 | LMNA (0.67) | KMT2ALMNAALDH1A1PKMPLA2G1B | |
| SCHEMBL2467120 | 0.79 | NPC1 (0.66) | KMT2AP2RX7LMNAALDH1A1PKM | |
| SCHEMBL13923294 | 0.77 | TSHR (0.69) | KMT2ALMNAALDH1A1PKMKDM4E | |
| SCHEMBL13923296 | 0.77 | HSD17B10 (0.72) | KMT2AALDH1A1PKML3MBTL1KDM4E | |
| SCHEMBL5243056 | 0.76 | PKM (0.81) | KMT2ALMNAALDH1A1PKML3MBTL1 | |
| SCHEMBL13408652 | 0.76 | ALDH1A1 (0.69) | KMT2AALDH1A1L3MBTL1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |