Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.30 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065597 | 1.00 | TYMS (0.35) | TYMSCDK1SRD5A1SRD5A2GABRA1 | |
| SCHEMBL883262 | 1.00 | TYMS (0.35) | TYMSCDK1SRD5A1SRD5A2GABRA1 | |
| SCHEMBL2065596 | 1.00 | TYMS (0.35) | TYMSCDK1SRD5A1SRD5A2GABRA1 | |
| SCHEMBL12328158 | 0.91 | GPR119 (0.31) | GPR119 | |
| SCHEMBL16440338 | 0.88 | SPR (0.33) | CDK1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL21334117 | 0.88 | SPR (0.33) | CDK1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10234322 | 0.87 | GABRG2 (0.33) | TYMSGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12295804 | 0.87 | GABRG2 (0.33) | TYMSGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2066099 | 0.86 | TYMS (0.39) | TYMSSRD5A1SRD5A2 | |
| SCHEMBL12295799 | 0.85 | GABRA5 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102633-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |