Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13477873 | 1.00 | HPGD (0.34) | HPGDHTTSMN1; SMN2MGLL | |
| SCHEMBL327627 | 0.91 | HPGD (0.34) | HPGDHTTSMN1; SMN2MGLL | |
| SCHEMBL15677157 | 0.87 | MGLL (0.31) | MGLL | |
| SCHEMBL277464 | 0.85 | ALDH1A1 (0.33) | MGLL | |
| SCHEMBL2607896 | 0.85 | MGLL (0.32) | MGLL | |
| SCHEMBL12421788 | 0.85 | HPGD (0.35) | HPGDHTTSMN1; SMN2MGLL | |
| SCHEMBL11955695 | 0.84 | PRKCA (0.30) | — | |
| SCHEMBL25754314 | 0.84 | CYP1A2 (0.35) | — | |
| SCHEMBL12107373 | 0.82 | MGLL (0.34) | HPGDHTTSMN1; SMN2MGLL | |
| SCHEMBL16299454 | 0.79 | CYP3A4 (0.33) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203132-A1 | PYRROLIDINYL GROUPS FOR ATTACHING CONJUGATES TO OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203132-A1 | PYRROLIDINYL GROUPS FOR ATTACHING CONJUGATES TO OLIGOMERIC COMPOUNDS | PHAX, RIOX2, RNMT | HPGD 2304/4885HTT 670/4885SMN1; SMN2 2989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.