Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 10/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727533 | 0.81 | ESRRA (0.40) | RORC | |
| SCHEMBL16355872 | 0.66 | IGF1R (0.58) | — | |
| SCHEMBL2006727 | 0.62 | CYP19A1 (0.48) | — | |
| SCHEMBL9156902 | 0.62 | BCL2 (0.58) | — | |
| SCHEMBL5085770 | 0.61 | ALDH1A1 (0.48) | — | |
| SCHEMBL26746242 | 0.61 | MPO (0.47) | — | |
| SCHEMBL13545699 | 0.61 | HTR1A (0.42) | — | |
| SCHEMBL8432324 | 0.61 | NPC1 (0.44) | — | |
| SCHEMBL2766286 | 0.61 | HTR1A (0.61) | — | |
| SCHEMBL17558601 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103710-A1 | SUBSTITUTED 4-HYDROXY-N- (4-HYDROXYPHENYL) INDOLES AS ESTROGENIC AGENTS | GLAXO GROUP LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |