Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633458 | 0.84 | KDM4E (0.49) | KDM4ELMNAGAAALDH1A1PKM | |
| SCHEMBL13749526 | 0.82 | ALDH1A1 (0.44) | KDM4ELMNAGAAALDH1A1PKM | |
| SCHEMBL13749459 | 0.79 | KDM4E (0.49) | KDM4ELMNAGAAALDH1A1PKM | |
| SCHEMBL13789387 | 0.72 | KDM4E (0.50) | KDM4ELMNAGAAALDH1A1PKM | |
| SCHEMBL14908004 | 0.69 | KDM4E (0.68) | KDM4ELMNAGAAALDH1A1PKM | |
| SCHEMBL19911645 | 0.68 | HTR6 (0.70) | KDM4ELMNAALDH1A1POLBMAPT | |
| SCHEMBL7836254 | 0.68 | HTR6 (0.76) | KDM4ELMNAGAAALDH1A1PKM | |
| SCHEMBL12903578 | 0.67 | SMN1; SMN2 (0.76) | KDM4ELMNAGAAALDH1A1PKM | |
| SCHEMBL28722730 | 0.67 | CA12 (0.56) | LMNAGAAALDH1A1CYTH2FFAR4 | |
| SCHEMBL26053720 | 0.67 | TDP1 (0.70) | LMNAALDH1A1POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737459-B1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2009-08-05 | — | — | EP | disclosed |