Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13749029 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4ELMNAGAAPKM | |
| SCHEMBL13749459 | 0.72 | KDM4E (0.49) | ALDH1A1KDM4ELMNAGAAPKM | |
| SCHEMBL13789387 | 0.70 | KDM4E (0.50) | ALDH1A1KDM4ELMNAGAAPKM | |
| SCHEMBL13633458 | 0.67 | KDM4E (0.49) | ALDH1A1KDM4ELMNAGAAPKM | |
| SCHEMBL7824834 | 0.66 | ALDH1A1 (0.78) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL13633551 | 0.65 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAGAAUSP2 | |
| SCHEMBL14908004 | 0.65 | KDM4E (0.68) | ALDH1A1KDM4ELMNAGAAPKM | |
| SCHEMBL7836254 | 0.64 | HTR6 (0.76) | ALDH1A1KDM4ELMNAGAAPKM | |
| SCHEMBL29002544 | 0.64 | NFKBIA (0.55) | ALDH1A1KDM4ELMNAHSD11B1SMN1; SMN2 | |
| SCHEMBL12903578 | 0.63 | SMN1; SMN2 (0.76) | ALDH1A1KDM4ELMNAGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737459-B1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2009-08-05 | — | — | EP | disclosed |