Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HTR6 | P50406 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836254 | 0.89 | HTR6 (0.76) | KDM4EALDH1A1LMNAHTR6MAPT | |
| SCHEMBL7835135 | 0.77 | HTR6 (1.00) | KDM4EALDH1A1LMNAHTR6MAPT | |
| SCHEMBL7824884 | 0.76 | HTR6 (0.74) | KDM4EALDH1A1LMNAHTR6MAPT | |
| SCHEMBL678897 | 0.76 | HTR6 (1.00) | KDM4EALDH1A1LMNAHTR6MAPT | |
| SCHEMBL7824099 | 0.76 | HTR6 (0.74) | KDM4EALDH1A1LMNAHTR6MAPT | |
| SCHEMBL7837566 | 0.75 | HTR6 (0.74) | KDM4EALDH1A1HTR6MAPTCYP3A4 | |
| Hydrochloric Acid SCHEMBL8054947 | 0.75 | MAPT (1.00) | KDM4EALDH1A1LMNAHTR6MAPT | |
| SCHEMBL1828300 | 0.74 | PDE4A (0.74) | KDM4EALDH1A1LMNAMAPTPDE4A | |
| Sulfisomidine SCHEMBL34791 | 0.74 | PDE4A (1.00) | KDM4EALDH1A1LMNAHTR6MAPT | |
| SCHEMBL7836431 | 0.74 | ALDH1A1 (0.71) | KDM4EALDH1A1LMNAHTR6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063269-A2 | COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS | CASE WESTERN RESERVE UNIVERSITY (US) | 2013-05-02 | — | — | WO | disclosed |