Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18098225 | 1.00 | ALDH1A1 (0.33) | ALDH1A1NPSR1HRH3ITGB3ITGA2B | |
| SCHEMBL12147633 | 0.82 | SLC6A4 (0.32) | — | |
| SCHEMBL29715079 | 0.77 | EPHX2 (0.39) | — | |
| SCHEMBL27756051 | 0.77 | EPHX2 (0.39) | — | |
| SCHEMBL29103272 | 0.76 | HDAC6 (0.36) | ALDH1A1NLRP3 | |
| SCHEMBL27756043 | 0.76 | PARP1 (0.33) | ALDH1A1 | |
| SCHEMBL27777020 | 0.75 | EPHX2 (0.37) | ALDH1A1 | |
| SCHEMBL16263829 | 0.75 | HDAC6 (0.34) | ALDH1A1NLRP3 | |
| SCHEMBL14200585 | 0.75 | HDAC6 (0.34) | ALDH1A1NLRP3 | |
| SCHEMBL30179278 | 0.75 | EPHX1 (0.34) | ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288111-A1 | INHIBITION OF INFLUENZA M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-11-24 | — | — | US | claimed |
| WO-2010033339-A1 | INHIBITION OF INFLUENZA M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-25 | — | — | WO | claimed |
| US-9453005-B2 | Inhibition of influenza M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-09-27 | — | — | US | disclosed |
| US-20110288111-A1 | INHIBITION OF INFLUENZA M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-11-24 | — | — | US | disclosed |
| WO-2010033339-A1 | INHIBITION OF INFLUENZA M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288111-A1 | INHIBITION OF INFLUENZA M2 PROTON CHANNEL | HVCN1, TRPM2, ASIC1 | ALDH1A1 2422/4885NPSR1 820/4885HRH3 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.