Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20717755 | 0.86 | ALDH1A1 (0.65) | SMN1; SMN2KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL13753789 | 0.85 | HPGD (0.51) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL13753637 | 0.85 | ATM (0.64) | SMN1; SMN2ALDH1A1L3MBTL1LMNARAB9A | |
| SCHEMBL13753638 | 0.84 | HPGD (0.64) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL13753786 | 0.83 | HPGD (0.65) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL13753788 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL13753787 | 0.82 | TAS1R3 (0.61) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL13753648 | 0.81 | NPSR1 (0.65) | ALDH1A1LMNARAB9AHTTKMT2A | |
| SCHEMBL13753288 | 0.80 | ALDH1A1 (0.61) | SMN1; SMN2KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL13753287 | 0.80 | ALDH1A1 (0.61) | SMN1; SMN2KDM4EMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |