Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753654 | 0.85 | SMN1; SMN2 (0.57) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753637 | 0.84 | ATM (0.64) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753638 | 0.83 | HPGD (0.64) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753786 | 0.82 | HPGD (0.65) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753788 | 0.81 | ALDH1A1 (0.59) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753781 | 0.81 | MLYCD (0.50) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753825 | 0.81 | MLYCD (0.50) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753835 | 0.81 | MLYCD (0.50) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753787 | 0.81 | TAS1R3 (0.61) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL13753809 | 0.80 | NPSR1 (0.56) | HPGDSMN1; SMN2LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |