Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474644 | 0.83 | NPY5R (0.44) | PTGS2RAD51KIF11F2RL3CYP2C9 | |
| SCHEMBL17259255 | 0.79 | KCNH2 (0.38) | PTGS2KIF11DYRK1ADYRK2DYRK3 | |
| SCHEMBL13757487 | 0.77 | MEN1 (0.51) | PTGS2P2RY6DYRK1ANPC1MAPT | |
| SCHEMBL17259268 | 0.73 | MAPT (0.47) | PTGS2MAPT | |
| SCHEMBL8684114 | 0.72 | NPY5R (0.41) | RAD51KIF11DYRK1ADYRK2DYRK3 | |
| SCHEMBL14557164 | 0.70 | ALDH1A1 (0.46) | PTGS2RAD51KIF11DYRK1ADYRK2 | |
| SCHEMBL4681659 | 0.70 | NPY5R (0.46) | PTGS2RAD51KIF11F2RL3CYP2C9 | |
| SCHEMBL1093634 | 0.70 | PTGS2 (0.43) | PTGS2CYP2C9 | |
| SCHEMBL2828552 | 0.69 | RAD51 (0.42) | PTGS2RAD51KIF11GLO1F2RL3 | |
| SCHEMBL13698757 | 0.69 | PTGS1 (0.59) | PTGS2P2RY6MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579348-B2 | Derivatives of 8-substituted xanthines | PGXHEALTH, LLC (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579348-B2 | Derivatives of 8-substituted xanthines | PGXHEALTH, LLC (US) | 2009-08-25 | — | — | US | disclosed |
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADENOSINE THERAPEUTICS, LLC | 2007-10-25 | — | — | US | disclosed |
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADENOSINE THERAPEUTICS, LLC | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADORA2B, ADORA2A, ADORA3 | PTGS2 648/4885P2RY6 20/4885RAD51 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.