Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629065 | 0.83 | FDPS (0.41) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL9927858 | 0.79 | SMN1; SMN2 (0.77) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL12220251 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Bromide SCHEMBL29479434 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL12220249 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Bromide SCHEMBL14765117 | 0.77 | SMN1; SMN2 (0.74) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL14499207 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL12220228 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| SCHEMBL12220261 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 | |
| Iodide SCHEMBL2530883 | 0.77 | SMN1; SMN2 (0.74) | SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576242-B2 | N-Ethylpyridinium bis(pentafluoroethyl)phosphinate; reacting tris(perfluoroalkyl)phosphine oxide is reacted with an alcohol and an organic base; ionic liquids | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |
| US-20070128515-A1 | Process for the preparation of organic salts containing bis(perfluoroalkyl) phosphinate anions | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070128515-A1 | Process for the preparation of organic salts containing bis(perfluoroalkyl) phosphinate anions | PHOSPHO1, PFAS, PFKFB1 | SMN1; SMN2 4516/4885MEN1 2001/4885HSP90AA1 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.