Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861744 | 0.80 | F10 (0.47) | F10 | |
| SCHEMBL8346713 | 0.80 | F10 (0.47) | F10HDAC6 | |
| SCHEMBL3865007 | 0.79 | F10 (0.40) | F10HDAC6 | |
| SCHEMBL3863014 | 0.78 | CSNK2A2 (0.49) | F10HDAC6 | |
| SCHEMBL3873919 | 0.76 | PDE2A (0.45) | F10 | |
| SCHEMBL4687144 | 0.75 | F10 (0.40) | F10HDAC6 | |
| SCHEMBL3868472 | 0.75 | F10 (0.73) | F10 | |
| SCHEMBL3868441 | 0.75 | F10 (0.40) | F10HDAC6 | |
| SCHEMBL8346292 | 0.74 | F10 (0.43) | F10 | |
| SCHEMBL8344703 | 0.72 | ALDH1A1 (0.46) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566789-B2 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2009-07-28 | — | — | US | disclosed |
| US-7566789-B2 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2009-07-28 | — | — | US | disclosed |