Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 14/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861744 | 0.85 | F10 (0.47) | F10 | |
| SCHEMBL8346292 | 0.80 | F10 (0.43) | F10 | |
| SCHEMBL8344662 | 0.78 | KDM4E (0.40) | F10 | |
| SCHEMBL3863014 | 0.77 | CSNK2A2 (0.49) | F10 | |
| SCHEMBL13759438 | 0.76 | F10 (0.43) | F10 | |
| SCHEMBL8346713 | 0.76 | F10 (0.47) | PDE2APDE3BPDE3AP2RY12F10 | |
| SCHEMBL8347891 | 0.75 | L3MBTL1 (0.47) | F10 | |
| SCHEMBL4687144 | 0.74 | F10 (0.40) | F10 | |
| SCHEMBL8344703 | 0.71 | ALDH1A1 (0.46) | F10 | |
| SCHEMBL8348316 | 0.70 | F10 (0.43) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566789-B2 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2009-07-28 | — | — | US | disclosed |
| US-20050272740-A1 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272740-A1 | Benzimidazole derivatives | F12, F11, SERPINC1 | PDE2A 2107/4885PDE3B 1410/4885PDE3A 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.