Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696331 | 0.84 | MAPT (0.40) | MAPTKMT2AMEN1NPSR1NPC1 | |
| SCHEMBL8213938 | 0.81 | MAPT (0.67) | MAPTKMT2AMEN1GAACYP1A2 | |
| SCHEMBL506668 | 0.81 | CYP1A2 (0.58) | KMT2AMEN1CYP1A2TDP1ALDH1A1 | |
| SCHEMBL26696336 | 0.80 | MET (0.55) | MAPTKMT2AMEN1POLBGAA | |
| SCHEMBL13763316 | 0.79 | GAA (0.51) | MAPTKMT2AMEN1NPSR1POLB | |
| SCHEMBL15111049 | 0.76 | ALDH1A1 (0.61) | MAPTKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL1849779 | 0.74 | NPC1 (0.51) | MAPTKMT2AMEN1GAANPC1 | |
| SCHEMBL28915757 | 0.73 | CLK1 (0.43) | MAPTKMT2AMEN1NPSR1POLB | |
| SCHEMBL3697952 | 0.72 | CYP1A2 (0.59) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31633570 | 0.72 | CYP1A2 (0.56) | MAPTKMT2AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791262-B2 | Asymmetric friedel-crafts alkylations catalyzed by bifunctional cinchona alkaloids | BRANDEIS UNIVERSITY (US) | 2014-07-29 | — | — | US | disclosed |
| US-20090203913-A1 | Asymmetric Friedel-Crafts Alkylations Catalyzed By Bifunctional Cinchona Alkaloids | BRANDEIS UNIVERSITY | 2009-08-13 | — | — | US | disclosed |
| WO-2007064861-A2 | ASYMMETRIC FRIEDEL-CRAFTS ALKYLATIONS CATALYZED BY BYFUNCTIONAL CINCHONA ALKALOIDS | BRANDEIS UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203913-A1 | Asymmetric Friedel-Crafts Alkylations Catalyzed By Bifunctional Cinchona Alkaloids | COASY, AANAT, PCNA | MAPT 4575/4885KMT2A 195/4885MEN1 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.