Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372752 | 0.75 | MAPT (0.42) | PDE4BPDE4DMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1375745 | 0.74 | MAPT (0.42) | PDE4BPDE4DMAPTMEN1KMT2A | |
| SCHEMBL1376319 | 0.71 | ELANE (0.44) | MAPTTP53POLBOXTR | |
| SCHEMBL9046046 | 0.71 | KMT2A (0.46) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL1375743 | 0.70 | MAPT (0.42) | PDE4BPDE4DMAPTMEN1KMT2A | |
| SCHEMBL4286400 | 0.70 | REN (0.44) | MAPTMEN1KMT2AOXTR | |
| SCHEMBL11668672 | 0.65 | MAPT (0.46) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL7432150 | 0.65 | RECQL (0.69) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL1374850 | 0.64 | MET (0.37) | PDE4BPDE4DMAPT | |
| SCHEMBL4958083 | 0.63 | LMNA (0.67) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | PDE4A 2273/4885PDE4B 2302/4885PDE4C 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.