Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MLYCD | O95822 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813341 | 0.83 | MLYCD (0.45) | ALDH1A1MLYCDSMN1; SMN2TSHRKDM4E | |
| SCHEMBL11155479 | 0.82 | MMP2 (0.49) | ALDH1A1MLYCDTDP1SMN1; SMN2HSD17B10 | |
| SCHEMBL13763795 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MLYCDTSHR | |
| SCHEMBL5353769 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MLYCDTSPOSMN1; SMN2TSHR | |
| SCHEMBL10175567 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TDP1PLK1SMN1; SMN2HPGD | |
| SCHEMBL13757710 | 0.79 | MLYCD (0.51) | ALDH1A1MLYCDTDP1SMN1; SMN2HSD17B10 | |
| SCHEMBL6908944 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MLYCDSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL10541028 | 0.77 | MLYCD (0.49) | ALDH1A1MLYCDSMN1; SMN2TSHRGAA | |
| SCHEMBL6907182 | 0.76 | PTPN1 (0.41) | ALDH1A1MLYCDTDP1TSPOSMN1; SMN2 | |
| SCHEMBL10540452 | 0.74 | MLYCD (0.46) | ALDH1A1MLYCDSMN1; SMN2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | GPR119, GCGR, GPBAR1 | ALDH1A1 1188/4885MLYCD 1982/4885TDP1 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.