Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.61 |
| ▸ | CA1 | P00915 | 8/20 | 0.61 |
| ▸ | CA9 | Q16790 | 6/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379606 | 0.87 | MAP3K11 (0.48) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL3367690 | 0.81 | CA1 (0.43) | CA2CA1CA9CA12MEN1 | |
| SCHEMBL1379771 | 0.80 | MAPT (0.37) | CA2CA1CA9CA12MEN1 | |
| SCHEMBL3368043 | 0.80 | TUBB4A (0.44) | CA2CA1CA9CA12MEN1 | |
| SCHEMBL1376476 | 0.79 | MAP3K11 (0.42) | MEN1MAPTKMT2ALMNAPOLB | |
| SCHEMBL1375792 | 0.76 | FYN (0.46) | CA2CA1CA9CA12MEN1 | |
| SCHEMBL1379148 | 0.74 | KDM4E (0.37) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL1375760 | 0.72 | CYP11B2 (0.48) | KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL3367727 | 0.72 | KMT2A (0.37) | CA2CA1CA9CA12MEN1 | |
| SCHEMBL3371555 | 0.72 | CA12 (0.43) | CA2CA1CA9CA12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4716996-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| EP-1628957-B1 | SULFOPYRROLES | TAKEDA PHARMACEUTICAL (JP) | 2010-09-29 | — | — | EP | claimed |
| US-20070060570-A1 | Sulfopyrroles | TALEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-15 | — | — | US | claimed |
| EP-1628957-A1 | SULFOPYRROLES | Takeda Pharmaceutical Company Limited (JP) | 2006-03-01 | — | — | EP | claimed |
| WO-2004103968-A1 | SULFOPYRROLES | APONETICS AG (CH) | 2004-12-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060570-A1 | Sulfopyrroles | TYK2, ARSA, SULT2A1 | CA2 3948/4885CA1 4547/4885CA9 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.