Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379286 | 0.86 | ALDH1A1 (0.45) | FYNMAPTLMNACA1CA2 | |
| SCHEMBL1375760 | 0.83 | CYP11B2 (0.48) | KMT2APOLBALPL | |
| SCHEMBL1378956 | 0.79 | CYP11B1 (0.47) | FYNMAPTLMNAMAP3K11ALPL | |
| SCHEMBL3371555 | 0.77 | CA12 (0.43) | MAPTLMNACA1CA2CA12 | |
| SCHEMBL1376420 | 0.76 | CA2 (0.61) | MAPTLMNACA1CA2CA12 | |
| SCHEMBL3369368 | 0.76 | TUBB1 (0.44) | MAPTLMNACA1CA2CA12 | |
| SCHEMBL5696246 | 0.75 | L3MBTL1 (0.47) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL20589457 | 0.73 | ABL1 (0.64) | FYNABL1FLT3MAP3K11LRRK2 | |
| SCHEMBL1379606 | 0.73 | MAP3K11 (0.48) | FYNCA1CA2CA12CA9 | |
| SCHEMBL5696178 | 0.72 | RAPGEF4 (0.53) | MAPTCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4716996-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| EP-1628957-B1 | SULFOPYRROLES | TAKEDA PHARMACEUTICAL (JP) | 2010-09-29 | — | — | EP | claimed |
| US-20070060570-A1 | Sulfopyrroles | TALEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-15 | — | — | US | claimed |
| EP-1628957-A1 | SULFOPYRROLES | Takeda Pharmaceutical Company Limited (JP) | 2006-03-01 | — | — | EP | claimed |
| WO-2004103968-A1 | SULFOPYRROLES | APONETICS AG (CH) | 2004-12-02 | — | — | WO | claimed |
| EP-1628957-B1 | SULFOPYRROLES | TAKEDA PHARMACEUTICAL (JP) | 2010-09-29 | — | — | EP | disclosed |
| US-7612064-B2 | Sulfopyrroles | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20070060570-A1 | Sulfopyrroles | TALEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1628957-A1 | SULFOPYRROLES | Takeda Pharmaceutical Company Limited (JP) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004103968-A1 | SULFOPYRROLES | APONETICS AG (CH) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060570-A1 | Sulfopyrroles | TYK2, ARSA, SULT2A1 | FYN 120/4885ABL1 23/4885FLT3 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.